The rapid development of 5G communications, wearables, sensors, and internet of things have pushed forward the need for all types of electronics and sensors requiring the exceptional properties of two-dimensional (2D) nanomaterials. Graphene and other 2D materials have become an increasingly interesting candidate in these systems due to the mechanical strength and flexibility at the ultimate materials scaling limit, unique transport characteristics, tunable optical properties, controllable surface sites and the potential for facile device fabrication. In this talk, challenges and opportunities to address scalability in 2D material transition metal dichalcogenides is presented. These techniques include low cost and customizable laser-manufacturing approaches and a two-step metal conversion process for direct synthesis of superlattices to allow material properties by design.