ICMCTF2016 Session D4: Smart/Intelligent Bio-Surfaces, Biosensors, Metal Ion/Particle Release, Clinical Side Effects

Tuesday, April 26, 2016 9:40 AM in Room Sunrise
Tuesday Morning

Time Period TuM Sessions | Abstract Timeline | Topic D Sessions | Time Periods | Topics | ICMCTF2016 Schedule

Start Invited? Item
9:40 AM D4-6 Influences of Niobium Contents on the Mechanical Property, Corrosion Resistance and Biocompatibility of Ternary Fe-Zr-Nb Thin Film Metallic Glasses
Tzu-Yao Lin, Jyh-Wei Lee (Ming Chi University of Technology, Taiwan, Republic of China); Bih-Show Lou (Chang Gung University, Taiwan, Republic of China)
Recently, the thin film metallic glasses (TFMGs) have drawn lots of attention from academia and industries due to their unique properties and possible applications. In this work, five newly developed ternary Fe-Zr-Nb TFMGs were fabricated on Si wafer and AISI420 stainless steel disk substrates using a magnetron co-sputtering system. The power of Nb target was adjusted to grow TFMGs with different Nb contents. The chemical compositions and microstructures of Fe-Zr-Nb TFMGs were analyzed by a field emission electron probe microanalyzer and field emission scanning electron microscopy, respectively. The amorphous phase of TFMG was determined by X-ray diffractometer (XRD) and transmission electron microscopy. The nanoindenter, scratch test and HRC-DB adhesion tester were employed to evaluate the mechanical and adhesion properties of coatings. Potentiodynamic polarization test in 5 wt.% NaCl aqueous solution was conducted to investigate the corrosion resistance of TFMGs. The MG-63 cell line (human osteosarcoma) was used to investigate cell-material interaction and biocompatibility of coatings. Effects of Nb contents on the hardness, adhesion, anti-corrosion performance and biocompatibility of the Fe-Zr-Nb TFMGs were discussed in this work.
10:00 AM Invited D4-7 Inkjet Printed Thin Film Technology for Wireless Biosensors
Bashir Morshed (University of Memphis, USA)

Inkjet printing is a relatively new technology for low temperature thin film depositions on planar substrates. This paper presents a number of wireless biosensor prototypes developed using this technology. The thin films were developed with a material deposition printer (Dimatix DMP-2831, FujiFilm Dimatix Inc., NH) on various flexible substrates including paper. The printed thin films were silver nanoparticles (Metalon JS-B25HV, Nanosilver Ink, Novacentrix, TX), copper oxide nanoparticles (Metalon ICI-002, Copper oxide Ink, Novacentrix, TX), and polypyrrole (Sigma Aldrich Co. LLC, St. Louis, MO). The average sizes of these nanoparticles were between 85 to 115 nm. The printing ink viscosities were between 3 to 10 cPa with 30% to 50% loading. The thicknesses of the silver nanoparticle films were in the range of 250 to 350 nm. The drop spacing was kept at 15 µm by setting the printer resolution to 1693 dpi. The trace widths for electrically conductive silver nanoparticle thin film were between 100 to 500 µm.

To manipulate track resistances or increase the thickness of insulation layers, multiple coatings of overlaying thin film deposition can be effectively employed, provided that a new coating is applied after the previous coating is fully cured. Multilayer circuits were also developed using copper oxide insulation layer sandwiched between two silver thin film traces. Vias were created by not printing any insulation layer in the via region, and applying multiple coatings of silver traces only inside these via cavities. The top surface irregularity of the insulation layer was minimized by limiting the droplet sizes using drop rates between 20 to 25 kHz.

This thin film printing technology was utilized to prototype fully passive wireless sensors for physiological biosignal monitoring with our proprietary technology - Resistive Wireless Analog Passive Sensors (rWAPS). The rWAPS circuits enjoy battery-less operation, low component count, fast response time, and low RF power requirement and is suitable for this printing technology. The prototypes were developed on flexible substrates as low-cost body-worn disposable electronic patches. The interrogator probes the sensors wirelessly at 13.65MHz using inductive coupling principle, and the resistive transducer at the sensors modulates the amplitude of the reflected wave, which can be decoded with envelope detectors. Ability to develop thin film multilayer printed circuits on flexible substrates coupled with the simplicity of the rWAPS system demonstrate the possibility of wear-and-forget type body-worn wireless biosensors to routinely monitor physiological signals for a multitude of biomedical applications.

10:40 AM D4-9 Production of AlN Thin Film Coatings for Biosensors
Abril Murillo, Lizbeth Melo-Máximo, Olimpia Salas, Joaquin Oseguera (ITESM-CEM, Mexico); Dulce Melo-Máximo (Termoinnova, S.a. De C.v., Mexico); Kevin Garcia (ITESM-CCM, Mexico)
AlN crystalline thin films have been deposited by r.f. reactive magnetron sputtering on various substrates as a first step in the developing of piezoelectric thin films for biosensors for early cancer detection. In this first stage, the effect of important deposition variables, partial pressure of N2, deposition time, and power, have been investigated. The results indicate a correlation between these variables and the structure of the coating, particularly the surface roughness and the crystal structure of the AlN. Detailed analysis of the present results will be the basis for the next step, deposition of the AlN films via HIPIMS (High Power Impulse Magnetron Sputtering).
Time Period TuM Sessions | Abstract Timeline | Topic D Sessions | Time Periods | Topics | ICMCTF2016 Schedule